Coronavirus is a deadly disease that turned into a global pandemic in March but appeared at the end of 2019 in Wuhan – China. Researchers and pharmaceutical companies around the globe are in the race to get palliative drugs and a vaccine. In this context, an investigation from Argentina is part of a very promising one. Today we’ll talk to you about the use of equine serum against coronavirus.
The coronavirus currently exceeds 17 million confirmed cases worldwide and the death toll is around 700,000. This alarming health emergency situation has led scientists from various countries to be fully trying to create a coronavirus vaccine.
Europe has already passed the strongest phase, although they cannot be neglected because a second wave may emerge. While in America the situation is very complicated as it is currently the epicenter of the pandemic.
Among the countries hardest hit by the coronavirus are the following: United States, Brazil, Mexico, Chile, Peru. The rest of the other countries behave with a large number of confirmed cases.
At the moment we have to continue complying to the letter with the preventive measures that we will mention later.
In Argentina, innovations are being made in relation to use equine serum against the coronavirus.
Preventive measures to avoid coronavirus
To prevent the spread of COVID-19 take care with this recommendation:
- Wash your hands often. Use soap and water or an alcohol-based hand sanitizer.
- Keep a safe distance from people who cough or sneeze.
- Wear the mask when it is not possible to maintain physical distance.
- Avoid touching your eyes, nose and mouth.
- When you cough or sneeze, cover your nose and mouth with your elbow flexed or with a tissue.
- If you are not feeling well, stay home.
- If you have a fever, cough, or shortness of breath, seek medical attention.
Argentina taking the lead in creating an equine serum against the coronavirus
Equine coronavirus serum represents a solution for this disease. For this reason the austral country began studies with serum obtained from horses.
This is intended to be used in the treatment of patients with coronavirus. The expectation is that it will strengthen as a powerful medicine against the disease.
It can also be used after the vaccine has been started.
Dr. Fernando Goldbaum said the following:
“Our horizon is October, November and December to produce tens of thousands of treatments to meet the needs of the Argentine health system”
This outstanding Argentinean is leading the pharmaceutical brand Inmunova. This is one of the venues representing the studio.
Argentina recently approved the research protocol for the clinical study of an equine serum to be used in patients with coronavirus.
The goal of this study is to validate the safety and validity of the equine serum against the coronavirus.
Second phase of testing of the equine serum against the coronavirus
This initiative has advanced and the phase 2/3 trial was recently authorized.
Therefore, it has already started in a Buenos Aires hospital and will be expanded by around 15 more clinics.
This equine coronavirus serum will be administered in 242 volunteer patients.
Relevant records will be made to see its effectiveness in people with coronavirus. Depending on their behavior, the results will be seen within approximately 60 days.
Dr. Fernando Goldbaum expressed the following:
“The use of this hyperimmune serum could be a way to generate a treatment in a fast, safe, effective and simple way to cover this time between the ideal that we all hope for, which is the development of the vaccine, and the use of convalescent plasma »
Advantages of equine serum against coronavirus
Among the advantages of the Equine Serum against the coronavirus is that donors are not needed as with plasma.
This aids in the production of the Equine Serum against the coronavirus in large quantities.
The trajectory of this treatment is more than a century in the effective use of equine serum as a treatment for different diseases. For this reason:
“Horses have an enormous capacity to produce antibodies”
It should be noted that when the pandemic arose, the laboratory was focused on producing a treatment for hemolytic uremic syndrome. However, the purpose changed, giving priority to the production of equine serum against the coronavirus.
Inmunova director Linus Spatz. He expressed the following:
“We started working as soon as the first cases were known, in mid-March, to work, and basically the project consisted of obtaining recombinant proteins, antigens of the virus. We immunized the first horses and saw that they had a high capacity to respond to the immune system “
In the study carried out, it was observed that the large amount of antibodies in the animals had the ability to block the coronavirus. Also to prevent it from entering the cells.
Administration of equine serum in patients with coronavirus
This initiative to administer equine serum to patients with coronavirus is also carried out in other countries.
The way to deliver this medicine to the patient is through two intravenous doses. In this sense, the time it takes is approximately one hour.
Gustavo Lopardo, infectious medicine doctor and coordinator of the clinical study expressed the following:
“One at the time of diagnosis and one 48 hours later. With strict controls to see for adverse effects and allergic reactions that are not expected to be frequent “
The purpose of the equine serum experiment is to demonstrate the clinical improvement of patients between 18 and 79 years of age.
On the other hand, it is expected that these patients will not need to be admitted to the intensive care units.
This Immunova Clinical Investigation will be carried out on hospitalized patients positive in PCR test results.
The Minister of Science and Technology of the Nation, Roberto Salvarezza indicated in this regard:
“It is a model that combines the contribution of the State with that of private technology-based companies”
If this experiment of equine serum against coronavirus is favorable in the recovery of patients with coronavirus, it will be implemented covering the internal demand of the country.
Later, it is planned to export to states in the region that are interested in this innovative and unique treatment.
Horses improve human lives
Once again we can see the contributions of horses in the lives of men.
Argentina bets once again to solve the recovery of patients with coronavirus with the Equine Serum.
Sources:
https://gustavomirabalcastro.online/actualidad/suero-equino-contra-el-coronavirus/
Do you want to know more about Gustavo Mirabal, Coronavirus or Horses? go to:
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